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GI-Biome System

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Leaky Gut

The Gut-Brain Axis

The Microbiome 

The Microbiome 

The Gut-Brain Axis

Leaky Gut

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The Communication Superhighway

While at first the concept might sound unusual, science has proven your gut and brain talk continually, carrying information back and forth, from brainstem to bowels, through the nervous system. The bidirectional communication system is called the gut-brain axis (GBA). Through this connection, the gut microbiota can signal the central nervous system influencing bodily functions like mood, immune response, digestion and heart rate.††

How the Microbiome Affects Our Moods and Behavior

Have you ever felt butterflies in your stomach? This sensation may be attributed to the network of 100 million nerve cells lining your gut. Your gut  has such a powerful influence that some call it the “second brain.” Your gut and brain are connected through chemicals called neurotransmitters. Many of these neurotransmitters are produced by your gut cells and the trillions of microbes living there.†††

Scientists have found many types of neurotransmitters that release chemicals and hormones that affect how we think, feel and behave. In fact, large amounts of serotonin are found in the gut which contribute to a feeling of happiness and aid GI digestion. Your gut microbes also produce gamma-aminobutyric acid (GABA), which helps you sleep and feel calm.†††

Furthermore, your microbiome supports microbial fermentation of dietary fibers in the lower intestine and manufactures butyrate, a short chain fatty acid. Butyrate provides fuel for cells in your gut lining, supports immune system functions of the colon wall and helps to protect the digestive tract.

Cell-to-Cell Communication

Modern science increasingly supports the cell-to-cell communication Mannatech pioneered more than 26 years ago. Research confirms what many schools of thought have suspected for centuries—the gut-brain axis is pivotal in controlling our mental, physical and emotional well-being.

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Leaky Gut

The Microbiome 

The Gut-Brain Axis

Leaky Gut

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† Carabotti, Marilia, Sciocco, Annunziata. “The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems.” Annals of Gastoenterology: 2016; 29(2):240.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367209/

†† Breit Sigrid, Kupferberg Aleksandra, Rogler Gerhard, Hasler Gregor. “Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders.” Frontiers in Psychiatry. March 13, 2018. 
https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00044/full 

††† Azab, Marwa, Ph.D. Gut Bacteria Can Influence Your Mood, Thoughts, and Brain. Posted Aug 07, 2019. 
https://www.psychologytoday.com/us/blog/neuroscience-in-everyday-life/201908/gut-bacteria-can-influence-your-mood-thoughts-and-brain

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